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Polycaprolactone is also used for splinting, modeling, and as a feedstock for prototyping systems such as fused filament fabrication 3D printers. PCL is prepared by ring opening polymerization of ε-caprolactone using a catalyst such as stannous octoate. However, when it comes to tissue engineering, PCL suffers from some shortcomings such as slow degradation rate, poor mechanical properties, and low cell adhesion. Through the stimulation of collagen production, PCL-based products are able to correct facial ageing signs such as volume loss and contour laxity, providing an immediate and long-lasting natural effect. A variety of drugs have been encapsulated within PCL beads for controlled release and targeted drug delivery.
It performs like gutta-percha, has similar handling properties, and for retreatment purposes may be softened with heat, or dissolved with solvents like chloroform. C, easily achieved by immersing in hot water. Firmicutes and proteobacteria can degrade PCL. Fabrication and Properties of Polycaprolactone Composites Containing Calcium Phosphate-Based Ceramics and Bioactive Glasses in Bone Tissue Engineering: A Review”.